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2016 Featured Talks » The role of the microenvironment in modulating tumor angiogenesis



The role of the microenvironment in modulating tumor angiogenesis


Napoleone Ferrara, MD
Moores Cancer Center








Napoleone Ferrara, MD
Senior Deputy Director for Basic Science
Distinguished Professor of Pathology
Distinguished Adjunct Professor of Ophthalmology
Distinguished Adjunct Professor of Pharmacology
Moores Cancer Center
University of California, San Diego


Dr. Ferrara earned his M.D. degree in 1981 from the University of Catania Medical School in Italy. After completing his postdoctoral research at the University of California, San Francisco, he joined Genentech Inc. in 1988. It is there where he spent nearly 25 years working on the isolation, molecular cloning and biological characterization of VEGF-A which resulted in the development of bevacizumab, the first anti-angiogenic agent to be approved by the FDA for cancer therapy. His research also led to the development of ranibizumab, which has been FDA-approved for the treatment of multiple intraocular neovascular disorders. In December 2012, Dr. Ferrara joined the University of California, San Diego as a Distinguished Professor of Pathology, Distinguished Adjunct Professor of Ophthalmology, and Senior Deputy Director for Basic Science of the Moores Cancer Center. He plans to continue his research focusing on the biology of angiogenesis and the identification of its regulators.

Dr. Ferrara has authored over 300 scientific publications, which have been cited over 70,000 times. He is also the recipient of numerous scientific awards, including the AACR Cain Memorial Award, the Lefoulon-Delalande-Institut de France Prize, the Passano Award, the General Motors Cancer Research Award, the ASCO Science of Oncology Award, the Pezcoller Foundation-AACR International Award, the Lasker-deBakey Clinical Medical Research Award, the Janssen Award for Biomedical Research, the Economist Innovation Award, the Breakthrough Prize in Life Sciences, the Antonio Champalimaud Vision Award and the Gairdner Foundation International Award. Dr. Ferrara has been an elected member of the National Academy of Sciences, USA since 2006 and most recently became an elected member of the National Academy of Medicine in 2015.