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2018 Symposium


The 14th Moores Cancer Center Industry/Academia Translational Oncology Symposium was held on Thursday, February 22, 2018.

Duane Roth Award Lecture
Engineered T-Cells: The Sky is the Limit

Carl June, MD

Richard W. Vague Professor Of Immunotherapy
Perelman School Of Medicine
University Of Pennsylvania

Keynote Speaker
A New Model for Translational Research in the Nonprofit Sector

Peter Schultz, PhD

Chief Executive Officer
California Institute for Biomedical Research


Opening Remarks
Ida Deichaite, PhD, UC San Diego Moores Cancer Center

Mutational Signatures for Cancer Treatment and Cancer Prevention
Ludmil Alexandrov, PhD, UC San Diego Moores Cancer Center

Duane Roth Award Presenter
David Brenner, MD, Dean, UC San Diego SOM & Health Sciences

Junior Scientist Presentation: Dual PI3K/BRD4 Inhibition as a Novel Therapeutic Strategy for Hepatocellular Carcinoma
Adam Burgoyne, MD, PhD, UC San Diego Moores Cancer Center

The New Generation of Antibody Drug Conjugates: Intersection of Target and Payload
Julia Coronella, PhD, Tanabe Research Labs

Moores Cancer Center Overview
Ezra Cohen, MD, UC San Diego Moores Cancer Center

Symposium Introduction
Ida Deichaite, PhD, UC San Diego Moores Cancer Center

In silico drug discovery of dual inhibitors of combinatorial synthetic lethality inhibitors in the era of precision medical oncology; proof of concept
Donald Durden, MD, PhD, UC San Diego Moores Cancer Center

Role of neutrophil-mediated inflammation in colorectal cancer
Napoleone Ferrara, MD, UC San Diego Moores Cancer Center

A Personalized Cancer Immunotherapy Paradigm: Simple solutions to address complex options for patients
Priti Hedge, PhD, Genentech

The Next Wave: BCMA Targeted CAR-T Cells for Multiple Myeloma
Kristen Hege, MD, Celgene

Welcome Remarks
Pradeep Khosla, PhD, Chancellor, UC San Diego

Moores Cancer Center Introduction
Scott Lippman, MD, UC San Diego Moores Cancer Center

Inhibition of Difficult to Drug Tumor Cell and Immuno-Oncology targets with Next Generation Antisense Inhibitors
Robert MacLeod, PhD, Ionis Pharmaceuticals

Systematic Mapping of Genetic Vulnerabilities in Cancer via Novel CRISPR-Cas9 Screening Methodologies
Prashant Mali, PhD, UC San Diego Moores Cancer Center

Patient Advocacy Presentation
Brian McCloskey, Patient Advocate

Targeting PARP in Prostate Cancer: Promise and Pitfalls
Rana McKay, MD, UC San Diego Moores Cancer Center

Patient Advocacy Presentation
Bryce Olson, Patient Advocate

Gene Control Approach to Manipulate Cell State: Sensitizing Cancer Cells to Antibody-mediated Attack
Dave Orlando, PhD, Syros Pharmaceuticals

Killing Cancer Stem Cells in Brain Cancer
Jeremy Rich, MD, UC San Diego Moores Cancer Center



2018 Symposium Featured Talks


Please enjoy the featured talks below from our recent symposium. Thank you!

Please note: These videos are for private viewing only. Any unintended use of the videos without consent is prohibited.

Keynote Presentation: Duane Roth Award Lecture
Engineering T-Cells: The Sky is the Limit


Carl June, MD
University of Pennsylvania School of Medicine




Keynote Presentation:
A New Model for Translational Research in the Nonprofit Sector


Peter Schultz, PhD
California Institute for Biomedical Research



Welcome Remarks


Ida Deichaite, PhD, Symposium Organizer, UC San Diego Moores Cancer Center
Pradeep Khosla, PhD, Chancellor, UC San Diego



Welcome Remarks


Thomas Kipps, MD, PhD
Symposium Chair, UC San Diego Moores Cancer Center





In silico drug discovery of dual inhibitors of combinatorial synthetic lethality inhibitors in the era of prevision medical oncology; proof of concept


Donald Durden, MD, PhD
UC San Diego Moores Cancer Center


A Personalized Cancer Immunotherapy Paradigm: simple solutions to address complex options for patients


Priti Hedge, PhD
Genentech



Mutational Signatures for Cancer Treatment and Cancer Prevention


Ludmil Alexandrov, PhD
UC San Diego Moores Cancer Center




A Patient Journey Through the Lens of a Digital Marketer


Brian McCloskey
Patient Advocate




Moores Cancer Center Overview


Ezra Cohen, MD
UC San Diego Moores Cancer Center





Inhibition of Difficult to Drug Tumor Cell and Immuno-Oncology targets with Next Generation Antisense Inhibitors


Robert MacLeod, PhD
Ionis Pharmaceuticals



Targeting PARP in Prostate Cancer: Promise and Pitfalls


Rana McKay, MD
UC San Diego Moores Cancer Center




Junior Faculty Presentation
Dual PI3K/BRS4 Inhibition as a Novel Therapeutic Strategy for Hepatocellular Carcinoma


Adam Burgoyne, MD, PhD
UC San Diego Moores Cancer Center



The New Generation of Antibody Drug Conjugates: Intersection of Target and Payload


Julia Coronella, PhD
Tanabe Research Labs




Gene Control Approach to Manipulate Cell State: Sensitizing Cancer Cells to Antibody-mediated attack


David Orlando, PhD
Syros Pharmaceuticals



Killing Cancer Stem Cells in Brain Cancer


Jeremy Rich, MD
UC San Diego Moores Cancer Center



We Thank Our 2018 Supporters: